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Johnson says that work at Johns Hopkins on the use of psilocybin in cancer patients suffering from anxiety and depression is even further along than that on addiction. His team is currently analysing the results from a phase II trial of psilocybin in 44 patients with depression and anxiety about death, stemming from a diagnosis of advanced-stage cancer. Johnson says that ‘mystical’ experiences, such as McGlothlin’s, seem to lead to better clinical outcomes. The results have not yet been published, but he says that “the data are very favourable”. “There are a huge number of hurdles still, a lot of money needs to be raised, a lot of regulators need to frame things so that this revolution can take place at scale,” said Henri Sant-Cassia, founding partner of the Conscious Fund, which invests in early-stage ventures in psychedelic medicine. “There will be lots of failures, there will be lots of trial and error and a lot of heartache. But, if everything aligns properly, I think it is inevitable that over time, psychedelic medicine—certainly some elements—of it will become firmly embedded in the mainstream.”
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